What is Vitamin B12?
Vitamin B12 (Cobalamin) is an essential vitamin needed for:
Brain and nerve development
Red blood cell formation
DNA synthesis
Why is B12 used in Autism?
Some children with autism may have:
Low B12 levels
Poor methylation (a biochemical process important for brain function)
Gut absorption problems
B12 is used as a supportive therapy, not a cure.
Possible Benefits in Autism
Research suggests that B12 may help some children with:
✅ Speech improvement
✅ Better eye contact
✅ Reduced irritability and hyperactivity
✅ Improved sleep
✅ Better attention and learning
✅ Reduced repetitive behaviors (in some cases)
What is it?
Vitamin B12 (cobalamin) is a water-soluble vitamin essential to the body.
Tablets may contain various forms of B12, such as cyanocobalamin, methylcobalamin, hydroxocobalamin, or adenosylcobalamin.
The tablet provides this vitamin in a concentrated dosage (for example, 500 µg, 1000 µg, etc.) which is much higher than the typical daily requirement
Mechanism & Role in the Body
B12 is required for red blood cell formation, DNA synthesis, and nervous system function.
It helps maintain the myelin sheath (a protective covering of nerves) and supports neurological health.
Also involved in protein, fat, and carbohydrate metabolism.
The body stores B12 (especially in the liver), and excess is excreted in urine because it is water-soluble.
Indications / Uses
A B12 tablet may be used when:
Dietary intake is insufficient (for example, in strict vegetarians or vegans).
There is impaired absorption of B12 in the digestive system (due to conditions like pernicious anemia, gastrointestinal surgery, Crohn’s disease, etc.).
To prevent or treat B12 deficiency, which can lead to anemia and neurological problems.
Dosage & Strengths
B12 tablets come in various strengths (e.g. 500 µg, 1000 µg, etc.)
The recommended dietary allowance (RDA) for most adults is about 2.4 µg per day.
Because absorption is limited (especially in those with absorption problems), tablets often deliver much more than RDA, so that enough is absorbed.
Side Effects & Safety
Generally considered safe when taken in appropriate doses.
Possible side effects include: headache, nausea, diarrhea, itching, or a tingling sensation.
High doses in healthy individuals rarely lead to serious toxicity because excess is excreted.
However, in certain medical conditions or when interacting with other medications, caution is needed.